The Arab awakening arguably represents the most important transformation of Middle Eastern politics since the end of colonialism. How will the regional powers adjust their foreign policies to the new regional environment is however still extremely uncertain. This uncertainty is partially due to the well-known inability of international relations scholars to make assured predictions, but also to the fact that the dynamics of foreign policy shifts are still widely overlooked and generally misunderstood in the scientific literature. Is ‘foreign policy change’ a mere adaptation to changes taking place in the domestic arena, as argued by most IR liberals? Or is foreign policy behaviour wholly dependent on the international distribution of power, as argued by realists? Or is there room for autonomous decisions that are not only reactions to exogenous sources of change, but are purposive and proactive actions in their own right? The Arab awakening will most likely be a crucial case study to test each of these hypotheses.